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Old 6th September 2012, 08:24 PM
MrsBeeks's Avatar
Boxer Booster
Join Date: Jun 2012
Location: Ontario, Canada
Posts: 253
Question about vomiting after Trifexis...

Hey there! I'm wondering if anyone could share their thoughts on whether I should re-dose Dutch for flea/heartworm/tick etc prevention.
Dutch was due today for his 3rd round of Trifexis, so I picked it up at the vet, and gave it to him between 4-4:30pm, then I fed him shortly after that. At about 6:30pm, Dutch started to get a wee bit agitated and then vomited all over the floor.....A LOT....then about 5 minutes later, he vomited again. This is the 3rd time he has received Trifexis, but the 1st time he has had any major issue from it, however, now that I read up a bit more about it, I think I will be switching him to Revolution instead.
Anyways, I called my vet to let them know, and they are recommending I bring him in on Monday to redose him with a different flea/heartworm etc control.....namely Sentinel. My question is.....would 2 hours not be enough time for the Trifexis to be into his system?? The Trifexis website says that if a dog vomits within an hour after taking the pill, then you should redose....but Dutch was a little more than 2 hours after.
I want to make sure he's protected, but I also don't want to re-dose if I don't have too.
What are your thoughts.
Dutch, flashy brindle boxer boy, born April 12, 2012, docked tail and floppy ears. :O)
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Old 6th September 2012, 09:08 PM
whiskers's Avatar
Boxer Insane
Join Date: Apr 2009
Location: Minnesota, USA
Posts: 1,591
If he vomited 2 hours after the fact I'd be inclined to believe it's probably not an effective dosing.

Personally, if this were my dog I would do a re-dosing of JUST a heartworm preventative. Usually, at least with the ivermectin-based preventatives, it is a suuuuuper low dosage so even if you re-dosed him, he's really not getting that much of the drug; even a dog sensitive to ivermectin could still take a Heartgard without any ill effects. I don't know how prevalent fleas/ticks are in your area, but they are not even on my list of concerns which is why I wouldn't mind taking my chances on that; he may have absorbed some if it, I don't know.

Or, I'd probably just do what the vet thought best.
Juno CGC - 3/31/09 Boxer :: Happy - 1/01 Border Collie Mix
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